| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | -1.63 | -31.17 | -42.67 | -61.69 | -81.83 | -85.30 | -98.80 | -98.16 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | -22.65 | -53.22 | -44.22 | -79.08 | -83.27 | -83.27 | -98.49 | -67.86 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | -7.63 | -5.11 | -26.70 | -25.34 | -50.31 | -52.65 | -30.23 | 3.95 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | -2.67 | 0.89 | 9.76 | -18.37 | -20.09 | -50.33 | -67.23 | -85.45 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | 2.88 | 4.61 | -17.37 | -15.61 | -37.43 | -38.28 | -59.41 | -44.19 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | 2.01 | 0.58 | -17.71 | -19.65 | -27.74 | -35.94 | -28.26 | -1.25 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | 2.77 | -2.71 | -28.81 | -28.05 | -34.66 | -33.69 | -47.37 | -60.57 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | 0.45 | 2.55 | -15.01 | -14.43 | -21.91 | -7.44 | -39.93 | -51.10 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | 1.58 | 6.93 | -10.73 | 8.66 | -5.72 | -5.60 | 4.01 | -12.51 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | 0.81 | 4.19 | -12.64 | 2.94 | -12.13 | 0.64 | -4.30 | 4.93 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | 0.71 | 8.59 | -12.59 | -2.61 | -17.58 | 7.60 | -6.96 | -33.21 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | -0.26 | -2.44 | -17.05 | -11.59 | -5.39 | 7.96 | -23.70 | -27.63 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | -1.89 | -1.46 | -12.57 | 2.73 | -12.31 | 8.21 | 19.06 | 20.97 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | 0.76 | 0.22 | -18.60 | 1.76 | -6.54 | 9.15 | 15.74 | 21.60 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | 2.31 | 5.90 | -3.30 | 7.96 | -2.72 | 12.26 | 1.12 | -3.16 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | 14.30 | 16.51 | 1.84 | 15.91 | -8.12 | 12.58 | 128.90 | 188.85 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | 0.67 | 2.50 | -13.61 | 0.32 | -7.22 | 13.74 | -0.43 | 4.82 |
| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | -12.25 | 11.30 | -13.06 | -22.40 | -13.86 | 15.94 | -87.35 | -87.35 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | 1.17 | 7.21 | -1.21 | 16.29 | -2.65 | 21.85 | 18.61 | 27.81 |
| | Medicus Pharma Ltd | Drug Manufacturers - General | Healthcare | 3.90 | 19.40 | 35.59 | 33.78 | 50.94 | 50.94 | 50.94 | 50.94 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | -0.32 | 3.10 | -6.88 | 14.63 | 21.52 | 62.06 | 34.80 | 90.81 |
