| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | -4.34 | 14.62 | -2.33 | -40.00 | -66.71 | -81.52 | -96.51 | -96.96 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | 0.00 | -0.20 | 0.05 | -52.38 | -54.25 | -74.99 | -91.30 | -35.98 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | -1.67 | -3.26 | -24.06 | -22.57 | -41.02 | -46.35 | -13.60 | 22.79 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | -0.46 | -6.86 | -7.76 | -14.13 | -29.26 | -36.67 | -52.87 | -38.24 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | -2.18 | -9.57 | -17.14 | -20.02 | -28.75 | -60.13 | -71.64 | -88.36 |
| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | -5.06 | -18.18 | -1.09 | -28.57 | -23.08 | -15.89 | -87.87 | -87.87 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | -5.07 | -2.74 | -17.13 | -8.02 | -20.56 | 3.19 | -1.11 | -41.58 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | -0.24 | -1.38 | -6.46 | -12.11 | -20.28 | -31.52 | -16.06 | 12.76 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | -1.83 | -0.76 | 0.70 | -4.69 | -17.98 | -14.03 | -30.12 | -50.74 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | -1.66 | -2.88 | -7.47 | -7.14 | -11.52 | -5.17 | -34.36 | -45.41 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | -3.56 | -3.97 | -15.13 | 1.06 | -10.61 | 2.33 | 128.28 | 178.25 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | 2.35 | 1.48 | -2.86 | 13.17 | -3.79 | 12.90 | 10.23 | 18.10 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | 1.24 | -0.53 | -3.36 | 13.44 | -1.66 | 17.35 | 10.24 | 18.13 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | 1.36 | 1.33 | -0.30 | 19.57 | -0.83 | 16.35 | 35.02 | 39.07 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | 1.35 | 0.77 | 3.83 | 17.63 | 0.95 | 21.71 | 27.18 | 36.73 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | 2.87 | -2.03 | -4.46 | 11.73 | 1.18 | 6.93 | 8.40 | -1.05 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | 3.64 | 1.27 | 2.79 | 17.83 | 3.93 | -2.29 | 17.45 | 0.31 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | -1.73 | -0.53 | -4.65 | 12.32 | 4.97 | 17.85 | 35.54 | 39.42 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | -2.99 | -1.83 | -3.42 | 2.21 | 9.06 | 16.35 | -9.45 | -12.55 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | 0.45 | 1.11 | -2.42 | 23.81 | 35.59 | 64.49 | 45.60 | 108.22 |
| | Medicus Pharma Ltd | Drug Manufacturers - General | Healthcare | 10.29 | 13.64 | -1.32 | 49.40 | 41.51 | 41.51 | 41.51 | 41.51 |
