| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | -2.32 | -18.90 | -43.72 | -55.52 | -50.32 | -41.80 | -88.86 | -94.10 |
| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | -0.40 | -16.00 | 20.00 | -36.36 | 23.53 | -67.69 | -83.02 | -83.02 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | 1.09 | -2.74 | -13.16 | -27.94 | -29.67 | 43.41 | -31.98 | -44.88 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | 1.68 | -1.20 | -17.02 | -24.89 | -18.35 | 2.08 | 2.41 | 21.30 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | -2.51 | -2.55 | -12.53 | -23.96 | -23.86 | 0.64 | 84.09 | 90.52 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | 1.29 | -4.17 | -14.43 | -23.36 | -30.60 | -31.17 | -47.61 | -37.35 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | -0.46 | -4.46 | -16.97 | -20.97 | -6.19 | 27.58 | 111.39 | 197.16 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | 6.17 | 0.94 | -8.71 | -19.00 | -41.46 | -31.75 | -54.36 | -86.11 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | 1.05 | -0.91 | -10.70 | -18.57 | -22.63 | -1.01 | 8.93 | -7.85 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | 2.48 | 1.53 | -6.09 | -13.36 | -22.66 | 0.29 | -0.28 | 33.52 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | 0.42 | 0.33 | -10.59 | -13.11 | -1.98 | 6.21 | 17.27 | 9.13 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | 0.76 | -3.42 | -11.79 | -12.09 | -9.38 | -11.99 | -42.67 | -44.30 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | 2.37 | 1.24 | -7.94 | -11.92 | 7.22 | 28.31 | 17.88 | 66.38 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | 0.74 | 0.44 | -10.27 | -11.70 | 0.98 | 10.39 | 24.40 | 38.33 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | 0.71 | -1.25 | -7.74 | -11.22 | -6.54 | 13.64 | 7.24 | 57.24 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | -7.14 | -13.33 | -13.28 | -9.97 | -14.93 | -21.52 | 100.00 | 66.45 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | 1.56 | 2.39 | -4.50 | -2.94 | 3.60 | 5.31 | -6.82 | 5.37 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | -0.70 | -10.58 | -0.35 | 11.34 | 11.34 | -10.58 | 9.35 | -26.88 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | 1.27 | -2.55 | 4.02 | 20.59 | 36.29 | 25.18 | 15.03 | 45.26 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | 0.60 | -0.46 | 11.72 | 21.56 | 41.42 | 26.18 | -19.76 | 14.52 |
