| Scilex Holding Co | Drug Manufacturers - General | Healthcare | -5.57 | -14.61 | -46.33 | -57.31 | -54.71 | -48.44 | -88.53 | -94.43 |
| Eli Lilly & Co | Drug Manufacturers - General | Healthcare | -0.25 | 0.24 | -17.46 | -21.35 | -6.40 | 26.72 | 111.02 | 196.40 |
| AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | 2.13 | 3.80 | -15.12 | -23.59 | -16.21 | 5.36 | 3.69 | 23.89 |
| Biogen Inc | Drug Manufacturers - General | Healthcare | -0.07 | -1.31 | -15.06 | -22.34 | -29.89 | -31.72 | -48.52 | -37.39 |
| Organon & Co | Drug Manufacturers - General | Healthcare | 2.62 | 1.66 | -10.37 | -25.56 | -28.19 | 44.42 | -30.51 | -43.44 |
| Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | 2.37 | 3.26 | -9.80 | -23.25 | -21.40 | 2.54 | 85.23 | 95.03 |
| Pfizer Inc | Drug Manufacturers - General | Healthcare | 2.07 | 3.43 | -9.68 | -9.49 | -10.76 | -10.23 | -42.55 | -43.15 |
| GSK Plc ADR | Drug Manufacturers - General | Healthcare | 0.77 | 1.83 | -9.63 | -18.14 | -24.28 | 0.26 | 8.44 | -7.14 |
| Sanofi ADR | Drug Manufacturers - General | Healthcare | 0.63 | 0.65 | -9.35 | -12.58 | -4.13 | 7.08 | 17.19 | 9.81 |
| Novartis AG ADR | Drug Manufacturers - General | Healthcare | 0.41 | 1.18 | -8.78 | -11.45 | 2.28 | 10.04 | 23.62 | 38.90 |
| Amgen Inc | Drug Manufacturers - General | Healthcare | 1.60 | 4.68 | -7.12 | -8.52 | -3.38 | 14.68 | 9.37 | 59.75 |
| Merck & Co Inc | Drug Manufacturers - General | Healthcare | -0.68 | 2.98 | -7.00 | -14.33 | -23.39 | 0.13 | -2.16 | 32.61 |
| AbbVie Inc | Drug Manufacturers - General | Healthcare | 3.04 | 7.25 | -6.26 | -9.17 | 12.78 | 32.46 | 19.42 | 71.43 |
| Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | 4.52 | 9.72 | -5.09 | -10.80 | -37.07 | -29.40 | -54.28 | -85.49 |
| Johnson & Johnson | Drug Manufacturers - General | Healthcare | -0.21 | 0.76 | -5.07 | -3.70 | 1.86 | 5.30 | -7.46 | 5.15 |
| Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | 1.87 | -8.13 | -1.36 | -1.69 | 21.00 | -9.94 | 9.02 | -25.51 |
| Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | 0.00 | 7.10 | 1.12 | -10.89 | -6.89 | -32.50 | -4.42 | 72.86 |
| Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | 0.48 | 2.02 | 2.30 | 19.94 | 35.91 | 24.10 | 14.39 | 45.96 |
| Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | 1.10 | 4.71 | 11.58 | 25.01 | 42.74 | 25.15 | -18.78 | 15.78 |
| MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | 4.76 | -14.29 | 25.71 | -29.41 | 44.17 | -58.69 | -82.21 | -82.21 |